Snips and Snails and Gender Stereotypes?

What are little boys made of?
Snips and snails, and puppy dogs tails
That’s what little boys are made of !”
What are little girls made of?
“Sugar and spice and all things nice
That’s what little girls are made of!”
This poem dates back to the early 19th century. Makes me wonder: How much of how boys are is nature versus nurture? How much of how little girls are is nature versus nurture?
What do you think?